Many methods of intradermal hyposensitization with insulin (in fact, immunization with insulin) have been proposed, largely differing in the rate of increasing the intradermal dose of insulin.


The rate of hyposensitization in the case of severe allergic reactions of the immediate type is determined primarily by the body's response to an increase in the dose of insulin.

  • Sometimes it is suggested to start with very high, almost homeopathic, dilutions (1:100,000, for example).
  • Desensitization techniques used today in the treatment of allergy to human insulin preparations and human insulin analogs have been described for a long time, including in my doctoral dissertation, which presents the results of my treatment of about 50 cases of a severe allergic reaction of an immediate type to all insulin preparations produced at that time.
  • Treatment is extremely burdensome for both the patient and the doctor, sometimes dragging on for several months.
Make sure you drink enough water during any exercise and during hot weather when you are taking Lasix, especially if you sweat a lot. If you do not drink enough water while taking Lasix, you may feel faint or light-headed or sick. This is because your blood pressure is dropping suddenly and you are dehydrating.

In the world practice of insulin therapy, four such cases are described, in two of which insulin therapy was carried out despite allergy, and the patients managed to wake up from a coma, and they did not develop an anaphylactic reaction, despite intravenous insulin administration. In two other cases, when doctors refrained from timely administration of insulin, the patients died from a diabetic coma.